Publications

• • (2021) Karagiannis A, Gallopin T, Lacroix A, Plaisier F, Piquet J, Geoffroy H, Hepp R, Naudé J, Le Gac B, Egger R, Lambolez B, Li D, Rossier J, Staiger JF, Imamura H, Seino S, Roeper J, Cauli B. Lactate is an energy substrate for rodent cortical neurons and enhances their firing activity. Elife. 2021 Nov 12;10:e71424. doi: 10.7554/eLife.71424. PMID: 34766906; PMCID: PMC8651295.

• • (2021) Bagur S, Lefort JM, Lacroix MM, de Lavilléon G, Herry C, Chouvaeff M, Billand C, Geoffroy H, Benchenane K. Breathing-driven prefrontal oscillations regulate maintenance of conditioned-fear evoked freezing independently of initiation. Nat Commun. 2021 May 10;12(1):2605. doi: 10.1038/s41467-021-22798-6. PMID: 33972521; PMCID: PMC8110519.

• • (2020) Laventure S, Benchenane K. Validating the theoretical bases of sleep reactivation during sharp-wave ripples and their association with emotional valence. Hippocampus. 2020 Jan;30(1):19-27. doi: 10.1002/hipo.23143. Epub 2019 Jul 23. PMID: 31334590.

• • (2019) Sauvet F, Gomez-Merino D, Dorey R, Ciret S, Gallopin T, Drogou C, Arnal PJ, Chennaoui M. Lengthening of the photoperiod influences sleep characteristics before and during total sleep deprivation in rat. J Sleep Res. 2019 Jun;28(3):e12709. doi: 10.1111/jsr.12709. Epub 2018 Jun 4. PMID: 29869353.

• • (2019) Tricoire L, Drobac E, Tsuzuki K, Gallopin T, Picaud S, Cauli B, Rossier J, Lambolez B. Bioluminescence calcium imaging of network dynamics and their cholinergic modulation in slices of cerebral cortex from male rats. J Neurosci Res. 2019 Apr;97(4):414-432. doi: 10.1002/jnr.24380. Epub 2019 Jan 3. PMID: 30604494.

• • (2018) Bagur S, Benchenane K. The Theta Rhythm Mixes and Matches Gamma Oscillations Cycle by Cycle. Neuron. 2018 Nov 21;100(4):768-771. doi: 10.1016/j.neuron.2018.11.008. PMID: 30465760.

• • (2018) Bagur S, Lacroix MM, de Lavilléon G, Lefort JM, Geoffroy H, Benchenane K. Harnessing olfactory bulb oscillations to perform fully brain-based sleep-scoring and real-time monitoring of anaesthesia depth. PLoS Biol. 2018 Nov 8;16(11):e2005458. doi: 10.1371/journal.pbio.2005458. PMID: 30408025; PMCID: PMC6224033.

• • (2018) Sauvet F, Gomez-Merino D, Dorey R, Ciret S, Gallopin T, Drogou C, Arnal PJ, Chennaoui M. Lengthening of the photoperiod influences sleep characteristics before and during total sleep deprivation in rat. J Sleep Res. 2018 Jun 4:e12709. doi: 10.1111/jsr.12709.

• • (2018) Slow-wave sleep: From the cell to the clinic.
    Léger D, Debellemaniere E, Rabat A, Bayon V, Benchenane K, Chennaoui M.
    Sleep Med Rev. 2018 Feb 5. pii: S1087-0792(17)30005-9. doi: 10.1016/j.smrv.2018.01.008.

• • (2017) Taming the oscillatory zoo in the hippocampus and neo-cortex: a review of the commentary of Lockmann and Tort on Roy et al.
    Bagur S, Benchenane K.
    Brain Struct Funct. 2018 Jan;223(1):5-9. doi: 10.1007/s00429-017-1569-x. Epub 2017 Dec 8.

• • (2017) Changes of Cerebral and/or Peripheral Adenosine A₁ Receptor and IGF-I Concentrations under Extended Sleep Duration in Rats.
    Chennaoui M, Arnal PJ, Dorey R, Sauvet F, Ciret S, Gallopin T, Leger D, Drogou C, Gomez-Merino D.
    Int J Mol Sci. 2017 Nov 17; 18(11). pii: E2439. doi: 10.3390/ijms18112439.

• • (2017) The homeostatic and circadian sleep recovery responses after total sleep deprivation in mice.
    Dispersyn G, Sauvet F, Gomez-Merino D, Ciret S, Drogou C, Leger D, Gallopin T, Chennaoui M.
    J Sleep Res. 2017 Oct;26(5):531-538. doi:10.1111/jsr.12541. Epub 2017 Apr 20.

• • (2016) 4-Hz oscillations synchronize prefrontal-amygdala circuits during fear behavior.
    Karalis N, Dejean C, Chaudun F, Khoder S, Rozeske RR, Wurtz H, Bagur S,
    Benchenane K., Sirota A, Courtin J, Herry C.
    Nat Neurosci. 19(4):605-12.

• • (2015) From necessity to sufficiency in memory research: when sleep helps to understand wake experiences.
    Lacroix MM, De Lavilléon G, Benchenane K.
    Curr Opin Neurobiol. 35:156-62.

• • (2015) Astroglial Connexin 43 Hemichannels Modulate Olfactory Bulb Slow Oscillations.
    Roux L, Madar A, Lacroix MM, Yi C, Benchenane K., Giaume C.
    J Neurosci. 35(46):15339-52.

• • (2015) Interaction Between Hippocampus and Cerebellum Crus I in
    Sequence-Based but not Place-Based Navigation.
    Iglói K, Doeller CF, Paradis AL, Benchenane K., Berthoz A, Burgess N,
    Rondi-Reig L.
    Cereb Cortex 25(11):4146-54.

• • (2015) Explicit memory creation during sleep demonstrates a causal role of place cells in navigation
    Gaetan de Lavilléon, Marie Masako Lacroix, Laure Rondi-Reig, Karim Benchenane
    Nat. Neurosci. 2015 Mar;09. doi:10.1038/nn.3970

• • (2014) Connexin 30 sets synaptic strength by controlling astroglial synapse invasion
    Pannasch U, Freche D, Dallérac G, Ghézali G, Escartin C, Ezan P, Cohen-Salmon M, Benchenane K, Abudara V, Dufour A, Lübke JH, Déglon N, Knott G, Holcman D, Rouach N.
    Nat. Neurosci. 2014 Apr;17(4):549-58. doi: 10.1038/nn.3662. Epub 2014 Mar 2.

• • (2011) Plasticity of astroglial networks in the olfactory glomeruli
    Roux L, Benchenane K, Rothstein J, Bonvento G, Giaume C.
    Proceedings of the National Academy of Science. Nov 8;108(45):18442-6.

• • (2011) The hippocampus: hub of brain network communication for memory
    Battaglia FP, Benchenane K, Sirota A, Pennartz CM, Wiener SI.
    Trends Cogn Sci. Jul;15(7):310-8. (review)

• • (2011) Spatial learning and action planning in a prefrontal cortical network model
    Martinet L-M, Sheynikhovich D, Benchenane K, Arleo. A
    Plos Comp Biol. May;7(5):e1002045.

• • (2011) Oscillations in the prefrontal cortex: a gateway to memory and attention
    Benchenane K, Tiesinga PH, Battaglia FP.
    Current Opinion Neurobiology. Jun;21(3):475-85. (review)

• • (2010) Coherent theta oscillations and reorganization of spike timing in the hippocampal-prefrontal network upon learning
    Benchenane K, Peyrache A, Khamassi M, Tierney PL, Gioanni Y, Battaglia FP, Wiener SI.
    Neuron. Jun 24;66(6):921-36.

• • (2010) Sequential reinstatement of neocortical activity during slow oscillations depends on cells’ global excitability.
    Peyrache A, Benchenane K, Khamassi M, Wiener SI, Battaglia FP.
    Frontiers in Systems Neuroscience, Jan; 3(18): 1-7.

• • (2009) Selective suppression of hippocampal ripples perturbes learning in a spatial reference memory task
    Girardeau G*, Benchenane K**, Wiener SI, Buzsáki G, Zugaro MB. **equal contribution
    Nat. Neurosci. Oct;12(10):1222-23.

• • (2009) Principal Component Analysis on ensemble recordings reveals cell assemblies at high temporal resolution
    Peyrache A, Benchenane K, Khamassi M, Wiener SI, Battaglia SP.
    J. Comput Neurosci. Jun 16.

• • (2009) Replay of rule-learning related neural patterns in the prefrontal cortex during sleep
    Peyrache A, Khamassi M, Benchenane K, Wiener SI, Battaglia SP.
    Nat Neurosci. Jul;12(7):919-26.

• • (2009) Fabrication technology for silicon based microprobe arrays used in acute and sub-chronic neural recording
    Herwik S, Kisban S, Seidl K, Girardeau G, Benchenane K, Zugaro MB, Wiener SI, Paul O, Ruther P.
    J. Micromech. Microeng. 19(7), June.

• • (2008) Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity.
    *Lopez-Atalaya JP, Roussel BD, Levrat D, Parcq J, Nicole O, Hommet Y, Benchenane K, Castel H, Leprince J, To Van D, Bureau R, Rault S, Vaudry H, Petersen KU, Santos JS, Ali C, Vivien D.
    J. Cereb Blood Flow Metab. Jun;28(6):1212-21.

• • (2007) Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms
    *Cacquevel M, Launay S, Castel H, Benchenane K, Chéenne S, Buée L, Moons L, Delacourte A, Carmeliet P, Vivien D.
    Neurobiol Dis. Aug;27(2):164-73.

• • (2007) Anti-NR1 N-terminal-domain vaccination unmasks the crucial action of tPA on NMDA-receptor- mediated toxicity and spatial memory
    *Benchenane K, Castel H, Boulouard M, Bluthé RM, Fernandez-Monreal M, Roussel BD, Lopez- Atalaya JP, Butt-Gueulle S, Agin V, Maubert E, Dantzer R, Touzani O, Dauphin F, Vivien D, Ali C.
    J. Cell Sci. Feb 15;120(Pt 4):578-85. Editor comment in the issue (February 15, 2007 J Cell Sci 120, e404.)

• • (2006) Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity
    *Liot G, Roussel BD, Lebeurrier N, Benchenane K, López-Atalaya JP, Vivien D, Ali C.
    J. Neurochem. Sep;98(5):1458-64.

• • (2005) Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis
    *Benchenane K, Berezowski V, Ali C, Fernández-Monreal M, López-Atalaya JP, Brillault J, Chuquet J, Nouvelot A, MacKenzie ET, Bu G, Cecchelli R, Touzani O, Vivien D.
    Circulation. May 3;111(17):2241-9.

• • (2005) Oxygen glucose deprivation switches the transport of tPA across the blood-brain barrier from an LRP-dependent to an increased LRP-independent process
    *Benchenane K, Berezowski V, Fernández-Monreal M, Brillault J, Valable S, Dehouck MP, Cecchelli R, Vivien D, Touzani O, Ali C.
    Stroke. May;36(5):1065-70.

• • (2004) [2,7-Bis-(4-amidinobenzylidene)-cycloheptan-1-one dihydrochloride, tPA stop, prevents tPA-enhanced excitotoxicity both in vitro and in vivo.
    *Liot G, Benchenane K, Léveillé F, López-Atalaya JP, Fernández-Monreal M, Ruocco A, Mackenzie ET, Buisson A, Ali C, Vivien D.
    J. Cereb Blood Flow Metab. Oct;24(10):1153-9.

• • (2004) Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling
    *Fernández-Monreal M, López-Atalaya JP, Benchenane K, Cacquevel M, Dulin F, Le Caer JP, Rossier J, Jarrige AC, Mackenzie ET, Colloc’h N, Ali C, Vivien D.
    J. Biol Chem. Dec 3;279(49):50850-6.

• • (2004) Is tissue-type plasminogen activator a neuromodulator?
    *Fernández-Monreal M, López-Atalaya JP, Benchenane K, Léveillé F, Cacquevel M, Plawinski L, MacKenzie ET, Bu G, Buisson A, Vivien D.
    Mol Cell Neurosci. Apr;25(4):594-601.

• • (2004) Equivocal roles of tissue-type plasminogen activator in stroke-induced injury. *Benchenane K, López-Atalaya JP, Fernández-Monreal M, Touzani O, Vivien D.
    Trends Neurosci. Mar;27(3):155-60. (review)

• • (2002) Selective blockade of endothelin-B receptors exacerbates ischemic brain damage in the rat
    *Chuquet J, Benchenane K, Toutain J, MacKenzie ET, Roussel S, Touzani O.
    Stroke. Dec;33(12):3019-25.

• • (2002) Matching gene expression with hypometabolism after cerebral ischemia in the nonhuman primate.
    *Chuquet J**, Benchenane K**, Liot G, Fernández-Monreal M, Toutain J, Blanchet S, Eveno E, Auffray C, Piétu G, Buisson A, Touzani O, MacKenzie ET, Vivien D. **equal contribution.
    J. Cereb Blood Flow Metab. Oct;22(10):1165-9.

(*: with PhD supervisor)

• • Battaglia FP, Benchenane K., Khamassi M., Peyrache A.,Wiener SI., (2008) "Neural Ensembles and Local Field Potentials in the Hippocampal-Prefrontal Cortex System During Spatial Learning and Strategy Shifts in Rats" in Advances in Cognitive Neurodynamics, Part II, Wang, Rubin; Gu, Fanji; Shen, Enhua (Eds.), p. 285-288.
    
  • Benchenane K., Zugaro MB., Wiener SI. (2008) "Neural Bases of Spatial Learning and Memory"
    in Encyclopedia of Neuroscience, Binder MD, Hirokawa N, Windhorst U (Eds). Springer, Berlin Heidelberg, p. 2552-2556.•
    
  • Vivien D., Benchenane K., Ali C. (2008) "Transforming Growth Factor-ß in Brain Functions and Dysfunctions"
    in Transforming Growth Factor-Beta in Cancer Therapy, Volume II, Chap 14, Jakowlew, Sonia (Ed.).
    

• • GDR Multielectrode System, Bordeaux, France. Octobre 2013
  • Lilly Company, Ascot, UK, July 2011
  • Ecole Supérieure de Physique et de Chimie Industrielles de la ville de Paris, May 2011
  • 10th International Meeting of the French Neuroscience Society
  • CNRS Thematic School, Cooperation and singularity in Biology, Berder, April 2011
  • Ecole Normale Supérieure
  • 5th CNRS-MPG joint workshop on Systems Biology, Dec 2010
  • Meeting of Computational Neuroscience (NeuroComp’10), Lyon, France, October 2010
  • Meeting of the French Sleep Society, Tours, France, Novembre 2010
  • Colloquium 2009 of the Research Group GDR 2905 NeuroMem, Oléron, France, May 2010
  • Journée “Maths et Cerveau”, Institut Henri Poincaré, Paris, March 2009
  • French Academy of Science, Paris, France. February 2009
  • Institute of Complex systems, Paris, France. January 2009
  • Network Synchronization: From dynamical systems to neuroscience, Leiden, The Netherlands, May 2008
  • Joint workshop ENS & Collège de France, Paris, France, October 2008
  • Colloquium 2008 of the Research Group GDR 2905 NeuroMem, Aussois, France, December 2008
  • Meeting ICEA, Integrating Cognition, Emotion and Autonomy IST-027819 ICEA

    , New Orleans, USA, November 2005.

Press

• • CNRS
    • CNRS International Magazine, January 2010 n°16 : Memory improves with sleep
    • CNRS Press release (May, 2009) : It really is best to sleep on it
    • CNRS Press release (June, 2010) : Ne retenir que ce qui est important
    • Journal du CRNS, november 2010, n°250, p. 11 : Du nouveau sur les mécanismes de notre mémoire

• • French national journal
    • Le Monde, June 13, 2009, p18
    • L’Humanité Dimanche, 3-9 February 2011, p80-81

• • French scientific review for the general public
    • La Recherche, September 2009, n°433, p26
    • Science et Vie, August 2009, n°1103, p15
    • L’Essentiel Cerveau et Psycho n° 6 May & July 2011, p60-65

Web

• • ScienceDaily, September 2009, Direct Evidence of the role of sleep in memory formation uncovered
  • National Geographic, September 2009, Direct Evidence of the role of sleep in memory formation uncovered

Radio

• • RTL (french national broadcast), June 01, 2009.
  • RSR (swiss national broadcast), July 01, 2009.