Nivea DE GUSMAO

Post-doctoral fellow

– Laboratoire Plasticité du Cerveau, CNRS UMR8249
ESPCI ParisTech
10 rue Vauquelin
75231 Paris cedex 5 France
– email :

Resumé

Pharmacist with a multidisciplinary background in neurosciences, epigenetics, and behavioral science. Holding a Ph.D. in Pharmacology, with a focus on stress, gene expression, and epigenetic changes in the prefrontal cortex, I combine expertise in pharmacology, and molecular biology with cutting-edge techniques such as optogenetics, calcium imaging, and receptor autoradiography. With a strong foundation in molecular biology, epigenetics, and neuropharmacology, I aim to better understand the brain, body, and their interactions in both health and disease.

ACADEMICS
2025- Postdoctoral Researcher – École Supérieure de Physique et de Chimie Industrielles de La Ville de Paris (ESPCI), Paris – France

▪ Brain Plasticity Laboratory
▪ Supervisor: Sophie BAGUR - Memory, Oscillations and Brain states team
▪ Main project: Study of the encoding of respiration in the mouse cortex by causal manipulation ▪
▪ Tools: Brain-Body interactions, Transgenic mice, Virus injection, Breathing manipulation, Immunohistochemistry, Optogenetics, Interoception.

2023-2025 Postdoctoral Resercher – Italian Institute of Techonology, Genoa – Italy

▪ Genetics and Epigenetics of Behavior Group
▪ Main project: Sleep influence on neuronal coding of time
▪ Tools: Genotyping, Virus injection, Stereotaxic surgery, Animal behaviour, Optogenetics, Reward-learning task, Calcium imaging, Immunohistochemistry, Confocal microscopy.

2016-2019 PhD in Sciences (Pharmacology) – University of São Paulo, São Paulo - Brazil

▪ Laboratory of Neurochemistry and Behavioral Pharmacology
▪ Main project: Environmental enrichment concomitant with unpredictable chronic stress induces anxiety-like behavior and decreases BDNF expression in mice prefrontal cortex
▪ Tools: Animal behaviour, Environmental enrichment, Stress models, Gene expression, Molecular biology, Biochemical and hormonal measurements, Epigenetic assays.

2014-2016 MSc in Health Sciences – Federal University of Alagoas, Maceió – Brazil

▪ Laboratory of Neuropharmacology and Integrative Physiology
▪ Main project: Crack: from psychostimulant effect to treatment, a new experimental model of drugs of abuse
▪ Tools: Animal behaviour, Drug addiction, Biochemical analysis, Brain section, Neurodegeneration assays, Histochemistry.

PUBLICATIONS LIST

Belo-Silva, A. E., de Gusmão Taveiros Silva, N. K., Marianno, P., de Araújo Costa, G., da Rovare, V. P., Bailey, A., Munhoz, C. D., Novaes, L. S., & Camarini, R. (2024). Effects of the combination of chronic unpredictable stress and environmental enrichment on anxiety-like behavior assessed using the elevated plus maze in Swiss male mice: Hypothalamus-Pituitary-Adrenal Axis-mediated mechanisms. Hormones and behavior, 162, 105538.
Effah, F., Nidadavolu, P., de Gusmão Taveiros Silva, N. K., Wojtowicz, M., Camarini, R., Zimmer, A., & Bailey, A. (2024). Differential temporal decline of cerebral oxytocin and μ-opioid receptor density during the aging process in mice. The European journal of neuroscience, 60(11), 6686–6703.
Costa, G. A., de Gusmão Taveiros Silva, N. K., Marianno, P., Chivers, P., Bailey, A., & Camarini, R. (2023). Environmental Enrichment Increased Bdnf Transcripts in the Prefrontal Cortex: Implications for an Epigenetically Controlled Mechanism. Neuroscience, 526, 277–289.
Effah, F., de Gusmão Taveiros Silva, N. K., Vijayanathan, K., Camarini, R., Joly, F., Taiwo, B., Rabot, S., Champeil-Potokar, G., Bombail, V., & Bailey, A. (2022). Sex-dependent impact of microbiota status on cerebral μ-opioid receptor density in fischer rats. The European journal of neuroscience, 55(8), 1917–1933.
Pacheco, A. L. D., de Melo, I. S., de Araujo Costa, M., Amaral, M. M. C., de Gusmão Taveiros Silva, N. K., Santos, Y. M. O., Gitaí, D. L. G., Duzzioni, M., Borbely, A. U., Silva, R. S., Donatti, A. L. F., Mestriner, L., Fuzo, C. A., Cummings, R. D., Garcia-Cairasco, N., Dias-Baruffi, M., & de Castro, O. W. (2022). Neuroprotective Effect of Exogenous Galectin-1 in Status Epilepticus. Molecular neurobiology, 59(12), 7354–7369.
Effah, F., de Gusmão Taveiros Silva, N. K., Camarini, R., Joly, F., Rabot, S., Bombail, V., & Bailey, A. (2021). Region-specific sex modulation of central oxytocin receptor by gut microbiota: An ontogenic study. Developmental neurobiology, 81(2), 149–163.
Araújo, M.S., Melo, I.S. Silva, N.K.G.T., Souza, F.M.A., Santos-Neto, J.G., Pacheco, A.L.D., Cavalcante, C.M.B., Freitas-Santos, J., Ferreira-Rodrigues, A.K.B., Silva, V.S., Basílio-Júnior, I.D., Santos, V.R., Gitaí, D.L.G., Bezerra, D.G., Duzzioni, M., Castro, O.W. (2018). Crack cocaine inhalation induces cardiac atrophy and facilitates limbic-motor seizures in mice submitted to subconvulsive dose of pilocarpine. International Journal of Advanced Scientific Research and Management (Online), 3, 7-11.
Melo, I. S., Santos, Y. M. O., Costa, M. A., Pacheco, A. L. D., Silva, N.K.G.T, Cardoso-Sousa, L., Pereira, U. P., Goulart, L. R., Garcia-Cairasco, N., Duzzioni, M., Gitaí, D. L. G., Tilelli, C. Q., Sabino-Silva, R., & Castro, O. W. (2016). Inhibition of sodium glucose cotransporters following status epilepticus induced by intrahippocampal pilocarpine affects neurodegeneration process in hippocampus. Epilepsy & behavior: E&B, 61, 258–268.
Viana M.D.M., Cardoso R.M., Silva, N.K.G.T., Falcão M.A.P., Vieira A.C.S., Alexandre-Moreira M.S., Campesatto E.A. Anxiolytic-like effect of Citrus limon (L.) Burm f. essential oil inhalation on mice. Rev. Bras. Plantas Med. 2016;18:96–104.

OTHER EXPERIENCES

2023-2023 – Temporary Lecturer (Pharmacology) – University of São Paulo, São Paulo – Brazil

2020-2023 – Academic Career break – Healthcare technology operations and clinical outcomes (Private company) – São Paulo – Brazil

2019-2020 – Interuniversity Exchange PhD (Neuropharmacology) – City St George’s, University of London, London – UK.

2019-2020 – Interuniversity Exchange PhD (Epigenetics) – University of Surrey, Guildford – UK.