ESPCI web site
– Pol E.*, Côme E.*, Merlaud Z., Gouhier J., Russeau M., Scotto-Lomassese S., Moutkine I., Marques X. and Lévi S.† (2023) NKCC1 and KCC2 chloride transporters have different membrane dynamics on the surface of hippocampal neurons. Cells 2023, 12(19), 2363 ; https://doi.org/10.3390/cells12192363
– Paupiah A.L., Marques X., Merlaud Z., Russeau M., Lévi S., Renner M. (2023) Introducing Diinamic, a flexible and robust method for clustering analysis in single-molecule localization microscopy. Biological Imaging, 3 : e14. https://doi.org/10.1017/S2633903X23000156
– Rimbert S., Moreira J. B., Xapelli S, Lévi S. †. (2023) Role of purines in brain development, from neuronal proliferation to synaptic refinement. Neuropharmacology. 2023 237:109640. doi : 10.1016/j.neuropharm.2023.109640.
– Côme E, Pol E, Merlaud Z, Gouhier J, Russeau M, Marques X, Scotto-Lomassese S, Moutkine I, and Lévi, S.†. (2022) The fast diffusion of NKCC1 along the axon is driven by glutamatergic activity. Preprint from bioRxiv, 13 Dec 2022. https://doi.org/10.1101/2022.12.11.519960 PPR : PPR583531
– Côme E., Blachier S., Gouhier J., Russeau M., and Lévi, S.†. (2023) Lateral Diffusion of NKCC1 Contributes to Chloride Homeostasis in Neurons and Is Rapidly Regulated by the WNK Signaling Pathway. Cells 2023, 12, 464. https://doi.org/10.3390/cells12030464
– Benhadda, A., Delhaye, C., Moutkine, I., Marques, X., Russeau, M., Le Magueresse, C., Roumier, A., Lévi, S., Maroteaux, L. (2023) 5-HT1A and 5-HT2B receptor interaction and co-clustering regulates serotonergic neuron excitability. iScience 26(8):107401. doi : 10.1016/j.isci.2023.107401. eCollection 2023 Aug 18. Preprint from bioRxiv. doi : https://doi.org/10.1101/2022.12.09.519723.
– Merlaud, Z. Marques, X., Russeau, M., Saade, U., Tostain, M., Moutkine, I., Gielen, M., Corringer, P.J. and Lévi, S.†. (2022) Conformational state-dependent regulation of GABAA receptor diffusion and subsynaptic domains. iScience 25, 105467. doi : 10.1016/j.isci.2022.105467. eCollection 2022 Nov 18.
– Lévi S†. & Bernard C†. (2022) Comment le cerveau élimine les synapses surnuméraires au cours du développement. How the brain gets rid of supernumerary synapses during development. Med Sci (Paris) 38, 511–513. https://doi.org/10.1051/medsci/2022076
– Boulin T, Itani O, El Mouridi S, Leclercq-Blondel A, Gendrel M, Macnamara E, Soldatos A, Murphy JL, Gorman MP, Lindsey A, Shimada S, Turner D, Silverman GA, Baldridge D. (2021) Undiagnosed Diseases Network, Malicdan MC, Schedl T, Pak SC. Functional analysis of a de novo variant in the neurodevelopment and generalized epilepsy disease gene NBEA. Mol Genet Metab. Sep-Oct ;134(1-2):195-202. https://doi.org/10.1016/j.ymgme.2021.07.013.
– Gomez Castro F*, Zappettini S*, Pressey J*, Silva CG, Russeau M, Gervasi N, Figueiredo M, Montmasson C, Renner M, Canas PM, Gonçalves FQ, Alçada-Morais S, Szabó E, Rodrigues RJ, Agostinho P, Tomé AR, Caillol G, Thoumine O, Nicol X, Letterrier C, Lujan R, Tyagarajan S, Cunha RA, Esclapez M, Bernard C†, Levi S†. (2021) Convergence of adenosine and GABA signaling for synapse stabilization during development. Science 374, eabk2055 PMID : 34735259 DOI : 10.1126/science.abk2055
– Benhadda A*, Quentin E*, Moutkine I, Chanrion B, Russeau M, Marin P, Levi S†, Maroteaux L.†. (2021) Serotonin 2B Receptor by Interacting with NMDA Receptor and CIPP Protein Complex May Control Structural Plasticity at Glutamatergic Synapses. ACS Chem. Neurosci. doi : 10.1021/acschemneuro.0c00638.
– Al Awabdh S, Donneger F, Goutierre M, Séveno M, Vigy O, Russeau M, Moutkine I, Marin P, Lévi S, Poncer JC†. (2022) Gephyrin interacts with the K-Cl co-transporter KCC2 to regulate its surface expression and function in cortical neurons J Neurosci. JN-RM-2926-20. doi : 10.1523/JNEUROSCI.2926-20.2021
– Côme E., Marques X., Poncer J.C., Lévi S†. (2020) Special issue : Neuronal protein mobility : KCC2 membrane
diffusion tunes neuronal chloride homeostasis. Neuropharmacology. 2020 Jun 1 ;169:107571. https://doi.org/10.1016/j.neuropharm.2019.03.014 ; Epub 2019 Mar 11. PMID : 30871970.
– Serrano-Saiz E, Gulez B, Pereira L, Gendrel M, Kerk SY, Vidal B, et al. (2020) Modular Organization of Cis-regulatory Control Information of Neurotransmitter Pathway Genes in Caenorhabditis elegans. Genetics. Jul ;215(3):665–81. https://doi.org/10.1534/genetics.120.303206.
– Carvalho K*, Faivre E*, Pietrowski MJ, Marques X, Gomez-Murcia V, Deleau A, Huin V, Hansen JN, Kozlov S, Danis C, Temido-Ferreira M, Coelho JE, Mériaux C, Eddarkaoui S, Le Gras S, Dumoulin M, Cellai L, NeuroCEB Brain Bank, Landrieu I, Chern Y, Hamdane M, Buée L, Boutillier AL, Levi S, Halle A, Lopes LV & Blum D†. (2019) Exacerbation of C1q dysregulation, synaptic loss and memory deficits in Tau pathology linked to neuronal adenosine A2A receptors. Brain 142(11):3636-3654. DOI : 10.1093/brain/awz288
– Bertin E, Deluc T, Pilch KS, Martinez A, Pougnet JT, Doudnikoff E, Allain AE, Bergmann P, Russeau M, Toulmé E, Bezard E, Koch-Nolte F, Séguéla P, Lévi S, Bontempi B, Georges F, Bertrand SS, Nicole O and Boué-Grabot E†. (2019) Increased surface P2X4 receptor expression regulates synaptic plasticity and behavior in P2X4 internalization-defective knock-in mice. Mol Psychiatry.2020 Jan 8. doi : 10.1038/s41380-019-0641-8.
– Côme E., Heubl M., Schwartz E.J., Poncer J.C., Lévi S†. (2019) Reciprocal Regulation of KCC2 Trafficking and Synaptic Activity. Front Cell Neurosci. 13:48. doi : 10.3389/fncel.2019.00048. eCollection 2019.
– Ben Soussia I*, Mouridi El S*, Kang D, Leclercq-Blondel A, Khoubza L, Tardy P, Zariohi N, Gendrel M, Lesage F, Kim EJ, Bichet D, Andrini O†, Boulin T†. (2019) Mutation of a Single Residue Promotes Gating of Vertebrate and Invertebrate Two-Pore Domain Potassium Channels. Nature Communications. Feb ; https://doi.org/10.1038/s41467-019-08710-3.
– Battaglia S, Renner M, Russeau M, Côme E, Tyagarajan S†, Lévi S†. (2018) Gephyrin phosphorylation conditions GABAAR membrane dynamics and homeostatic plasticity. eNeuro 2018 Jan 18 ;5(1). pii : ENEURO.0203-17.2017. https://doi.org/10.1523/ENEURO.0203-17.2017 eCollection 2018 Jan-Feb.
– Heubl M, Zhang J, Pressey J, Al Awabdh S, Renner M, Gomez Castro F, Moutkine I, Eugene E, Russeau M, Kahle KT, Poncer JC, Levi S†. (2017) GABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl—sensitive WNK1 kinase. Nat Commun. 8, 1776-. https://doi.org/10.1038/s41467-017-01749-0
– Renner M, Wang L, Lévi S, Hennekinne L, Triller A†. (2017) A simple and powerful analysis of lateral subdiffusion using single particle tracking. Biophys J. 113:2452-2463.
– Kepa A, Martinez Medina L, Erk S, Srivastava DP, Fernandes A, Toro R, Lévi S, Ruggeri B, Fernandes C, Degenhardt F, Witt SH, Meyer-Lindenberg A, Poncer JC, Martinot JL, Paillère Martinot ML, Müller CP, Heinz A, Walter H, Schumann G, Desrivières S. (2017) Associations of the Intellectual Disability Gene MYT1L with Helix-Loop-Helix Gene Expression, Hippocampus Volume and Hippocampus Activation During Memory Retrieval. Neuropsychopharmacology 42, 2516-2526. Epub 2017 May 4. DOI : 10.1038/npp.2017.91
– Serrano-Saiz E*†, Pereira L*†, Gendrel M*†, Aghayeva U, Bhattacharya A, Howell K, Garcia LR, Hobert O†. (2017) A Neurotransmitter Atlas of the Caenorhabditis elegans Male Nervous System Reveals Sexually Dimorphic Neurotransmitter Usage. Genetics. Jul ; https://doi.org/10.1534/genetics.117.202127.
– Gendrel M†, Atlas EG, Hobert O†. (2016) A cellular and regulatory map of the GABAergic nervous system of C. elegans. Elife. Oct 14 ;5:1395. https://doi.org/10.7554/eLife.17686.
– Chevy Q, Heubl M, Goutierre M, Backer S, Moutkine I, Eugène E, Bloch-Gallego E, Lévi S, Poncer JC†. (2015) KCC2 gates activity-driven AMPA receptor traffic through cofilin phosphorylation. J Neurosci. 35,15772-86. DOI : 10.1523/JNEUROSCI.1735-15.2015
– Bannai H., Niwa F., Sherwood MW., Shrivastava AN, Arizono M., Miyamoto A., Sugiura K., Lévi S., Triller A†. and Mikoshiba K†. (2015) Bidirectional Control of Synaptic GABAAR Clustering by Glutamate and Calcium. Cell Rep. Epub 2015 Dec 17. DOI : 10.1016/j.celrep.2015.12.002
– Lévi S†, Le Roux N, Eugène E, Poncer JC. (2015) Benzodiazepine ligands rapidly influence GABAA receptor diffusion and clustering at hippocampal inhibitory synapses. Neuropharmacology 88:199-208. DOI : 10.1016/j.neuropharm.2014.06.002
– Chamma I, Heubl M, Chevy Q, Renner M, Moutkine I, Eugène E, Poncer JC, Lévi S†. (2013) Activity-dependent regulation of the K/Cl transporter KCC2 membrane diffusion, clustering, and function in hippocampal neurons. J Neurosci. 33,15488-503. DOI : 10.1523/JNEUROSCI.5889-12.2013
– Buonanno M, Garty G, Grad M, Gendrel M, Hobert O, Brenner DJ. (2013) Microbeam irradiation of C. elegans nematode in microfluidic channels. Radiat Environ Biophys. Nov ;52(4):531–7. https://doi.org/10.1007/s00411-013-0485-6.
– Renner M, Schweizer C, Bannai H, Triller A†, Lévi S† (2012) Diffusion barriers constrain receptors at synapses. PLoS One. 7(8):e43032. Epub 2012 Aug 13. DOI : 10.1371/journal.pone.0043032
– Chamma I., Chevy Q., Poncer JC, Lévi S†. Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission. (2012) Front Cell Neurosci. 6:5. DOI : 10.3389/fncel.2012.00005
– Bouthour W.*, Leroy F.*, C. Emmanuelli, M. Carnaud, M. Dahan, JC Poncer, S. Lévi†. A Human Mutation in Gabrg2 Associated with Generalized Epilepsy Alters the Membrane Dynamics of GABAA Receptors. (2011) Cereb Cortex 22,1542-53. DOI : 10.1093/cercor/bhr225
– Gauvain G., Chamma I.*, Chevy Q.*, Cabezas C., Irinopoulou T., Bodrug N., Carnaud M., Lévi S. †, Poncer JC†. The neuronal K-Cl cotransporter KCC2 influences postsynaptic AMPA receptor content and lateral diffusion in dendritic spines. (2011) Proc Natl Acad Sci USA 108, 15474-9. DOI : 10.1073/pnas.1107893108
– Sancar F, Touroutine D, Gao S, Oh HJ, Gendrel M, Bessereau JL, Kim H, Zhen M, Richmond JE. (2011) The dystrophin-associated protein complex maintains muscle excitability by regulating Ca(2+)-dependent K(+) (BK) channel localization. J Biol Chem. Sep 23 ;286(38):33501–10. https://doi.org/10.1074/jbc.M111.227678.
*, equal contribution ; †, corresponding author
